Oxindole-Based Inhibitors of Cyclin-Dependent Kinase 2 (CDK2): Design, Synthesis, Enzymatic Activities, and X-ray Crystallographic Analysis
Author:
Affiliation:
1. GlaxoSmithKline Inc., Five Moore Drive, Research Triangle Park, North Carolina 27709
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm010117d
Reference59 articles.
1. CYCLIN-DEPENDENT KINASES: Engines, Clocks, and Microprocessors
2. Stein, G.; Baserga, R.; Giordano, A.; Denhardt, D. T.The Molecular Basisof Cell Cycle and Growth Control; John Wiley & Sons: New York, 1998; p 389.
3. Cyclins and cyclin-dependent kinases: take your partners
4. The Vitek analyser for routine bacterial identification and susceptibility testing: protocols, problems, and pitfalls
5. Mechanisms of cyclin-dependent kinase regulation: structures of cdks, their cyclin activators, and cip and INK4 inhibitors
Cited by 259 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Kinematic analysis of kinases and their oncogenic mutations – Kinases and their mutation kinematic analysis;Molecular Informatics;2024-06
2. Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships;European Journal of Medicinal Chemistry;2024-05
3. Exploring pyrrolidinyl-spirooxindole natural products as promising platforms for the synthesis of novel spirooxindoles as EGFR/CDK2 inhibitors for halting breast cancer cells;Frontiers in Chemistry;2024-02-29
4. Accelerating and Automating the Free Energy Perturbation Absolute Binding Free Energy Calculation with the RED-E Function;Journal of Chemical Information and Modeling;2023-12-04
5. Recent Development in the Search for Epidermal Growth Factor Receptor (EGFR) Inhibitors based on the Indole Pharmacophore;Current Topics in Medicinal Chemistry;2023-10-31
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3