Alkaline Phosphatase Catalysis Is Ultrasensitive to Charge Sequestered between the Active Site Zinc Ions
Author:
Affiliation:
1. Departments of Chemical Engineering, Chemistry, and Biochemistry, Stanford University, Stanford, California 94305
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja051603j
Reference33 articles.
1. Reaction mechanism of alkaline phosphatase based on crystal structures
2. A Model of the Transition State in the Alkaline Phosphatase Reaction
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4. Alkaline Phosphatase Revisited: Hydrolysis of Alkyl Phosphates
5. Two-Metal Ion Catalysis in Enzymatic Acyl- and Phosphoryl-Transfer Reactions
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