Discovery of 4-Aryl-4H-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-based High-Throughput Screening Assay. 1. Structure−Activity Relationships of the 4-Aryl Group-Reference-Cited by-同舟云学术

Discovery of 4-Aryl-4H-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-based High-Throughput Screening Assay. 1. Structure−Activity Relationships of the 4-Aryl Group

Published:2004-11-09 Issue:25 Volume:47 Page:6299-6310
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kemnitzer William¹,Drewe John¹,Jiang Songchun¹,Zhang Hong¹,Wang Yan¹,Zhao Jianghong¹,Jia Shaojuan¹,Herich John¹,Labreque Denis¹,Storer Richard¹,Meerovitch Karen¹,Bouffard David¹,Rej Rabindra¹,Denis Real¹,Blais Charles¹,Lamothe Serge¹,Attardo Giorgio¹,Gourdeau Henriette¹,Tseng Ben¹,Kasibhatla Shailaja¹,Cai Sui Xiong¹

Affiliation:

1. Maxim Pharmaceuticals, Inc., 6650 Nancy Ridge Drive, San Diego, California 92121, and Shire Biochem Inc., 275 Armand-Frappier Blvd., Laval, Quebec H7V 4A7, Canada

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm049640t

Reference26 articles.

1. Survivin: Role in Normal Cells and in Pathological Conditions

2. Apoptosis in the Pathogenesis and Treatment of Disease

3. Neuroprotection by the Inhibition of Apoptosis

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