Bioisosteric Heterocyclic Versions of 7-{[2-(4-Phenyl-piperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol: Identification of Highly Potent and Selective Agonists for Dopamine D3 Receptor with Potent in Vivo Activity-Reference-Cited by-同舟云学术

Bioisosteric Heterocyclic Versions of 7-{[2-(4-Phenyl-piperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol: Identification of Highly Potent and Selective Agonists for Dopamine D3 Receptor with Potent in Vivo Activity

Published:2008-04-12 Issue:10 Volume:51 Page:3005-3019
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Biswas Swati¹,Hazeldine Stuart¹,Ghosh Balaram¹,Parrington Ingrid¹,Kuzhikandathil Eldo¹,Reith Maarten E. A.¹,Dutta Aloke K.¹

Affiliation:

1. Department of Pharmaceutical Sciences, Wayne State University, Detroit, Michigan 48202, Department of Psychiatry, Millhauser Laboratories, New York University School of Medicine, New York, New York 10016, and Department of Pharmacology and Physiology, UMDNJ-New Jersey Medical School, Newark, New Jersey 07103

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm701524h

Reference53 articles.

1. Wooten, G. F.Movement Disorders. Neurologic Principles and Practice;McGraw-Hill:New York,1997; pp153−160.

2. Recent advances in the genetics and pathogenesis of Parkinson disease

3. MOLECULAR PATHOPHYSIOLOGY OF PARKINSON'S DISEASE

4. The Neuropathologic Basis of Different Clinical Subgroups of Parkinson's Disease

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