Role of Hydrophobic Modification in Spermine-Based Poly(β-amino ester)s for siRNA Delivery and Their Spray-Dried Powders for Inhalation and Improved Storage-Reference-Cited by-同舟云学术

Role of Hydrophobic Modification in Spermine-Based Poly(β-amino ester)s for siRNA Delivery and Their Spray-Dried Powders for Inhalation and Improved Storage

Published:2024-06-12 Issue:7 Volume:25 Page:4177-4191
ISSN:1525-7797
Container-title:Biomacromolecules
language:en
Short-container-title:Biomacromolecules

Author:

Jin Yao¹,Wang Xiaoxuan¹^ORCID,Kromer Adrian P.E.¹,Müller Joschka T.¹,Zimmermann Christoph¹,Xu Zehua²,Hartschuh Achim²³^ORCID,Adams Friederike¹^ORCID,Merkel Olivia M.¹³^ORCID

Affiliation:

1. Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 Munich, Germany

2. Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 Munich, Germany

3. Center for Nanoscience (CeNS), Ludwig-Maximilians-Universität München, 80799 München, Germany

Funder

Center for NanoScience, Ludwig-Maximilians-Universit?t M?nchen

China Scholarship Council

H2020 European Research Council

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biomac.4c00283

Reference47 articles.

1. Overcoming Barriers for siRNA Therapeutics: From Bench to Bedside

2. Current Aspects of siRNA Bioconjugate for In Vitro and In Vivo Delivery

3. Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

4. Overcoming cellular barriers for RNA therapeutics

5. GENETICS OF HUMAN CELL LINES, IV. DNA-MEDIATED HERITABLE TRANSFORMATION OF A BIOCHEMICAL TRAIT

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1. Alternative routes for parenteral nucleic acid delivery and related hurdles: highlights in RNA delivery;Expert Opinion on Drug Delivery;2024-09-13

2. Design of Experiments Grants Mechanistic Insights into the Synthesis of Spermine-Containing PBAE Copolymers;ACS Applied Materials & Interfaces;2024-07-10