Evaluation of the Tetrakis(3-Hydroxy-4-Pyridinone) Ligand THPN with Zirconium(IV): Thermodynamic Solution Studies, Bifunctionalization, and in Vivo Assessment of Macromolecular 89Zr-THPN-Conjugates-Reference-Cited by-同舟云学术

Evaluation of the Tetrakis(3-Hydroxy-4-Pyridinone) Ligand THPN with Zirconium(IV): Thermodynamic Solution Studies, Bifunctionalization, and in Vivo Assessment of Macromolecular 89Zr-THPN-Conjugates

Published:2019-10-21 Issue:21 Volume:58 Page:14667-14681
ISSN:0020-1669
Container-title:Inorganic Chemistry
language:en
Short-container-title:Inorg. Chem.

Author:

Buchwalder Christian¹^ORCID,Jaraquemada-Peláez María de Guadalupe²^ORCID,Rousseau Julie³,Merkens Helen³,Rodríguez-Rodríguez Cristina¹⁴^ORCID,Orvig Chris²^ORCID,Bénard François³^ORCID,Schaffer Paul⁵,Saatchi Katayoun¹,Häfeli Urs O.¹^ORCID

Affiliation:

1. University of British Columbia, Faculty of Pharmaceutical Sciences, 2405 Wesbrook Mall, Vancouver, BC V6T 1Z3, Canada

2. Medicinal Inorganic Chemistry Group, University of British Columbia, Department of Chemistry, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada

3. BC Cancer Agency, Department of Functional Imaging, 600 West 10th Avenue, Vancouver, BC V5Z 4E6, Canada

4. University of British Columbia, Department of Physics & Astronomy, 6224 Agricultural Road, Vancouver, BC V6T 1Z1, Canada

5. TRIUMF, Life Sciences Division, 4004 Wesbrook Mall, Vancouver, BC V6T 2A3, Canada

Funder

Canadian Institutes of Health Research

Natural Sciences and Engineering Research Council of Canada

University of British Columbia

Lundbeckfonden

Publisher

American Chemical Society (ACS)

Subject

Inorganic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.inorgchem.9b02350

Reference84 articles.

1. Immuno-Positron Emission Tomography with Zirconium-89-Labeled Monoclonal Antibodies in Oncology: What Can We Learn from Initial Clinical Trials?

2. 89Zr-ImmunoPET companion diagnostics and their impact in clinical drug development

3. 89Zr, a Radiometal Nuclide with High Potential for Molecular Imaging with PET: Chemistry, Applications and Remaining Challenges

4. PET imaging with 89Zr: From radiochemistry to the clinic

5. Recent Advances in Zirconium-89 Chelator Development

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