Keap Calm, and Carry on Covalently
Author:
Affiliation:
1. School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, U.K.
2. GlaxoSmithKline, 709 Swedeland Road, King of Prussia, Pennsylvania 19406, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm400224q
Reference139 articles.
1. An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements
2. Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene
3. Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1
4. Novel insights into the regulation of antioxidant-response-elementmediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2
5. Keap1 Controls Postinduction Repression of the Nrf2-Mediated Antioxidant Response by Escorting Nuclear Export of Nrf2
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