Regio- and Enantioselective Iridium-Catalyzed Amination of Racemic Branched Alkyl-Substituted Allylic Acetates with Primary and Secondary Aromatic and Heteroaromatic Amines
Author:
Affiliation:
1. Department of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States
2. Discovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States
Funder
Welch Foundation
Genentech
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/jacs.8b12152
Reference73 articles.
1. Enantioselective iridium-catalyzed carbonyl allylation from the alcohol oxidation level via transfer hydrogenation: minimizing pre-activation for synthetic efficiency
2. Catalytic Enantioselective CH Functionalization of Alcohols by Redox-Triggered Carbonyl Addition: Borrowing Hydrogen, Returning Carbon
3. Catalytic Enantioselective Carbonyl Allylation and Propargylation via Alcohol-Mediated Hydrogen Transfer: Merging the Chemistry of Grignard and Sabatier
4. Catalytic nucleophilic ‘umpoled’ π-allyl reagents
5. Catalytic C−C Coupling via Transfer Hydrogenation: Reverse Prenylation, Crotylation, and Allylation from the Alcohol or Aldehyde Oxidation Level
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