Do Two Different Reaction Mechanisms Contribute to the Hydroxylation of Primary Amines by Cytochrome P450?
Author:
Affiliation:
1. Department of Medicinal Chemistry, Copenhagen University, Universitetsparken 2, DK-2100 Copenhagen, Denmark
Publisher
American Chemical Society (ACS)
Subject
Physical and Theoretical Chemistry,Computer Science Applications
Link
https://pubs.acs.org/doi/pdf/10.1021/ct200422p
Reference30 articles.
1. N-OXIDATIVE TRANSFORMATION OF FREE ANDN-SUBSTITUTED AMINE FUNCTIONS BY CYTOCHROME P450 AS MEANS OF BIOACTIVATION AND DETOXICATION
2. Role of specific cytochrome P450 enzymes in the N-oxidation of the antiarrhythmic agent mexiletine
3. Oxidation of Cycloalkylamines by Cytochrome P-450
4. DRUG-MEDIATED INACTIVATION OF CYTOCHROME P450
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