Targeted LC-MS/MS Proteomics-Based Strategy To Characterize in Vitro Models Used in Drug Metabolism and Transport Studies-Reference-Cited by-同舟云学术

Targeted LC-MS/MS Proteomics-Based Strategy To Characterize in Vitro Models Used in Drug Metabolism and Transport Studies

Published:2018-09-11 Issue:20 Volume:90 Page:11873-11882
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Xu Meijuan¹²,Saxena Neha¹,Vrana Marc¹,Zhang Haeyoung¹,Kumar Vineet¹,Billington Sarah¹,Khojasteh Cyrus³,Heyward Scott⁴,Unadkat Jashvant D.¹,Prasad Bhagwat¹^ORCID

Affiliation:

1. Department of Pharmaceutics, University of Washington, Seattle, Washington 98195, United States

2. Department of Clinical Pharmacology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210029, China

3. Drug Metabolism and Pharmacokinetics Department, Genentech, Inc., South San Francisco, California 94080, United States

4. BioIVT, Baltimore, Maryland 21227, United States

Funder

University of Washington

Genentech

Eunice Kennedy Shriver National Institute of Child Health and Human Development

China Clinical Evaluation Research Institute

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.8b01913

Reference47 articles.

1. Simulation and prediction of in vivo drug metabolism in human populations from in vitro data

2. Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver

3. Covariation of Human Microsomal Protein Per Gram of Liver with Age: Absence of Influence of Operator and Sample Storage May Justify Interlaboratory Data Pooling

4. Aldehyde Oxidase: An Enzyme of Emerging Importance in Drug Discovery

5. Challenges and Opportunities with Non-CYP Enzymes Aldehyde Oxidase, Carboxylesterase, and UDP-Glucuronosyltransferase: Focus on Reaction Phenotyping and Prediction of Human Clearance

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