Separation of Plasmid DNA Topological Forms, Messenger RNA, and Lipid Nanoparticle Aggregates Using an Ultrawide Pore Size Exclusion Chromatography Column-Reference-Cited by-同舟云学术

Separation of Plasmid DNA Topological Forms, Messenger RNA, and Lipid Nanoparticle Aggregates Using an Ultrawide Pore Size Exclusion Chromatography Column

Published:2023-09-25 Issue:40 Volume:95 Page:15017-15024
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Goyon Alexandre¹^ORCID,Tang Shijia¹^ORCID,Fekete Szabolcs²^ORCID,Nguyen Daniel¹,Hofmann Kate¹,Wang Shirley¹^ORCID,Shatz-Binder Whitney³^ORCID,Fernandez Kiel Izabelle³,Hecht Elizabeth S.⁴,Lauber Matthew⁵,Zhang Kelly¹^ORCID

Affiliation:

1. Synthetic Molecule Analytical Chemistry, Genentech, 1 DNA Way, South San Francisco, California 94080, United States

2. Consumables and Lab Automation, Waters Corporation, CMU-Rue Michel Servet 1, Geneva 4 1211, Switzerland

3. Pharmaceutical Development, Genentech, 1 DNA Way, South San Francisco, California 94080, United States

4. Microchemistry, Proteomics, and Lipidomics, Genentech, 1 DNA Way, South San Francisco, California 94080, United States

5. Consumables and Lab Automation, Waters Corporation, 34 Maple Street, Milford, Massachusetts 01757, United States

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c02944

Reference26 articles.

1. Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA

2. Gene Therapy Progress and Prospects: Electroporation and other physical methods

3. Expression of transfected DNA depends on DNA topology

4. 〈1047〉 Gene Therapy Products

5. Effective and robust plasmid topology analysis and the subsequent characterization of the plasmid isoforms thereby observed

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