19F Dark-State Exchange Saturation Transfer NMR Reveals Reversible Formation of Protein-Specific Large Clusters in High-Concentration Protein Mixtures-Reference-Cited by-同舟云学术

19F Dark-State Exchange Saturation Transfer NMR Reveals Reversible Formation of Protein-Specific Large Clusters in High-Concentration Protein Mixtures

Published:2019-02-25 Issue:7 Volume:91 Page:4702-4708
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Edwards John M.¹,Bramham Jack E.¹,Podmore Adrian²,Bishop Steven M.³,van der Walle Christopher F.²^ORCID,Golovanov Alexander P.¹^ORCID

Affiliation:

1. Manchester Institute of Biotechnology and School of Chemistry, Faculty of Science and Engineering, The University of Manchester, Manchester M1 7DN, United Kingdom

2. Dosage Form Design & Development, AstraZeneca plc, Granta Park, Cambridge CB21 6GH, United Kingdom

3. Biopharmaceutical Development, AstraZeneca plc, Gaithersburg, Maryland 20878, United States

Funder

Biotechnology and Biological Sciences Research Council

MedImmune

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.analchem.9b00143

Reference40 articles.

1. What Macromolecular Crowding Can Do to a Protein

2. Liquid-Liquid Phase Separation in Biology

3. Physicochemical Properties of Cells and Their Effects on Intrinsically Disordered Proteins (IDPs)

4. The therapeutic monoclonal antibody market

5. Therapeutic antibodies: Market considerations, disease targets and bioprocessing

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Fluorinated Tags to Study Protein Conformation and Interactions Using ¹⁹F NMR;ChemBioChem;2024-06-24

2. Spectroscopically dark phosphate features revealed by chemical exchange saturation transfer;NMR in Biomedicine;2023-10-18

3. The improving strategies and applications of nanotechnology-based drugs in hepatocellular carcinoma treatment;Frontiers in Bioengineering and Biotechnology;2023-09-21

4. Phosphates form spectroscopically dark state assemblies in common aqueous solutions;Proceedings of the National Academy of Sciences;2022-12-29

5. Structural Insight into the Slowly Exchanging Dark States at the Functional Interaction Interface;NMR Spectroscopy for Probing Functional Dynamics at Biological Interfaces;2022-08-17