Ion-Based Proteome-Integrated Solubility Alteration Assays for Systemwide Profiling of Protein–Molecule Interactions-Reference-Cited by-同舟云学术

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Ion-Based Proteome-Integrated Solubility Alteration Assays for Systemwide Profiling of Protein–Molecule Interactions

Published:2022-05-04 Issue:19 Volume:94 Page:7066-7074
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Beusch Christian M.¹,Sabatier Pierre¹^ORCID,Zubarev Roman A.¹²³^ORCID

Affiliation:

1. Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm 17177, Sweden

2. Department of Pharmacological & Technological Chemistry, I.M. Sechenov First Moscow State Medical University, Moscow 119146, Russia

3. The National Medical Research Centre for Endocrinology, Moscow 115478, Russia

Funder

Ministry of Science and Higher Education of the Russian Federation

Cancerfonden

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.2c00391

Reference45 articles.

1. Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials

2. The target landscape of clinical kinase drugs

3. Know your target, know your molecule

4. Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay

5. Target profiling of small molecules by chemical proteomics

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