Unbiased Scanning Method and Data Banking Approach Using Ultra-High Performance Liquid Chromatography Coupled with High-Resolution Mass Spectrometry for Quantitative Comparison of Metabolite Exposure in Plasma across Species Analyzed at Different Dates
Author:
Affiliation:
1. Pharmacokinetics, Dynamics and Metabolism and ‡Biostatistics, Pfizer Inc., Groton, Connecticut 06340, United States
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.5b03469
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4. Optimization of Exactive Orbitrap™ acquisition parameters for quantitative bioanalysis
5. Cassette incubation followed by bioanalysis using high-resolution MS for in vitro ADME screening assays
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