1. Institute of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung 202, Taiwan; Institute of Plant and Microbial Biology, Academia Sinica, Nankang, Taipei 11529, Taiwan; Department of Biotechnology, Ming Chuan University, 5 De-Ming Road, Gweishan District, Taoyuan 333, Taiwan; and Department of Food Science and Biotechnology, National Chung Hsing University, Taichung 402, Taiwan