Pyrene·Pyrene Complexes at the Active Site of Cytochrome P450 3A4: Evidence for a Multiple Substrate Binding Site-Reference-Cited by-同舟云学术

Pyrene·Pyrene Complexes at the Active Site of Cytochrome P450 3A4: Evidence for a Multiple Substrate Binding Site

Published:2002-09-14 Issue:40 Volume:124 Page:11866-11867
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Dabrowski Michael J.¹,Schrag Michael L.¹,Wienkers Larry C.¹,Atkins William M.¹

Affiliation:

1. Department of Medicinal Chemistry, Box 357610, University of Washington, Seattle, Washington 98195-7610, Global Drug Metabolism, Pharmacia Corporation, Kalamazoo, Michigan 49007, and Department of Drug Metabolism, Merck Research Labs, West Point, Pennsylvania

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja027552x

Reference23 articles.

1. CYTOCHROME P-450 3A4: Regulation and Role in Drug Metabolism

Cited by 92 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The molecular basis of dapsone activation of CYP2C9-catalyzed nonsteroidal anti-inflammatory drug oxidation;Journal of Biological Chemistry;2023-12

2. 3site Multisubstrate-Bound State of Cytochrome P450cam;Journal of the American Chemical Society;2023-10-23

3. Nanodisc-embedded cytochrome P450 P3A4 binds diverse ligands by distributing conformational dynamics to its flexible elements;Journal of Inorganic Biochemistry;2023-07

4. Discovery of a Novel 3site State as the Multi-Substrate Bound State of P450cam;2023-03-16

5. Midazolam as a Probe for Drug–Drug Interactions Mediated by CYP3A4: Homotropic Allosteric Mechanism of Site-Specific Hydroxylation;Biochemistry;2021-05-20