A Series of Potent and Selective, Triazolylphenyl-Based Histone Deacetylases Inhibitors with Activity against Pancreatic Cancer Cells and Plasmodium falciparum-Reference-Cited by-同舟云学术

A Series of Potent and Selective, Triazolylphenyl-Based Histone Deacetylases Inhibitors with Activity against Pancreatic Cancer Cells and Plasmodium falciparum

Published:2008-05-22 Issue:12 Volume:51 Page:3437-3448
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chen Yufeng¹,Lopez-Sanchez Miriam¹,Savoy Doris N.¹,Billadeau Daniel D.¹,Dow Geoffrey S.¹,Kozikowski Alan P.¹

Affiliation:

1. Drug Discovery Program, Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, Division of Experimental Therapeutics, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Springs, Maryland 20910, and Department of Immunology, Division of Oncology Research, Mayo Clinic College of Medicine, 13-42 Guggenheim, 200 First Street SW, Rochester, Minnesota 55905

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm701606b

Reference51 articles.

1. Histone acetyltransferases and deacetylases in the control of cell proliferation and differentiation

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4. Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

5. HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription

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