Synthesis and Evaluation of Radioligands for Imaging Brain Nociceptin/Orphanin FQ Peptide (NOP) Receptors with Positron Emission Tomography-Reference-Cited by-同舟云学术

Synthesis and Evaluation of Radioligands for Imaging Brain Nociceptin/Orphanin FQ Peptide (NOP) Receptors with Positron Emission Tomography

Published:2011-03-25 Issue:8 Volume:54 Page:2687-2700
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pike Victor W.¹,Rash Karen S.²,Chen Zhaogen²,Pedregal Concepción³,Statnick Michael A.²,Kimura Yasuyuki¹,Hong Jinsoo¹,Zoghbi Sami S.¹,Fujita Masahiro¹,Toledo Miguel A.³,Diaz Nuria³,Gackenheimer Susan L.²,Tauscher Johannes T.²,Barth Vanessa N.²,Innis Robert B.¹

Affiliation:

1. Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room B3 C346A, 10 Center Drive, Bethesda, Maryland 20892, United States

2. Eli Lilly & Co., Lilly Research Laboratories, Indianapolis, Indiana 46285, United States

3. Lilly S.A., Avenida de la Industria 30, 28108-Alcobendas, Madrid, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm101487v

Reference38 articles.

1. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

2. Orphanin FQ: A Neuropeptide That Activates an Opioidlike G Protein-Coupled Receptor

3. The nociceptin/orphanin FQ receptor: a target with broad therapeutic potential

4. The Nociceptin/Orphanin FQ System as a Target for Treating Alcoholism

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