A New Class of Symmetric Bisbenzimidazole-Based DNA Minor Groove-Binding Agents Showing Antitumor Activity-Reference-Cited by-同舟云学术

A New Class of Symmetric Bisbenzimidazole-Based DNA Minor Groove-Binding Agents Showing Antitumor Activity

Published:2000-12-07 Issue:2 Volume:44 Page:138-144
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Mann John¹,Baron Anne¹,Opoku-Boahen Yaw¹,Johansson Eric¹,Parkinson Gary¹,Kelland Lloyd R.¹,Neidle Stephen¹

Affiliation:

1. Chemistry Department, Reading University, Whiteknights, Reading RG6 6AD, U.K., CRC Centre for Cancer Therapeutics, Institute of Cancer Research, Sutton, Surrey SM2 5NG, U.K., and CRC Biomolecular Structure Unit, Chester Beatty Laboratories, Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm000297b

Reference41 articles.

1. Dicationic Diarylfurans as Anti-Pneumocystis carinii Agents

2. Targeting the Minor Groove of DNA: Crystal Structures of Two Complexes between Furan Derivatives of Berenil and the DNA Dodecamer d(CGCGAATTCGCG)2

3. 2,5-Bis[4-(N-alkylamidino)phenyl]furans as Anti-Pneumocystis carinii Agents

4. 2,4-Diphenyl Furan Diamidines as Novel Anti-Pneumocystis carinii Pneumonia Agents

5. Cytotoxicity of bis(phenylamidinium)furan alkyl derivatives in human tumour cell lines: Relation to DNA minor groove binding

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