Algal Toxin Goniodomin A Binds Potassium Ion Selectively to Yield a Conformationally Altered Complex with Potential Biological Consequences-Reference-Cited by-同舟云学术

Algal Toxin Goniodomin A Binds Potassium Ion Selectively to Yield a Conformationally Altered Complex with Potential Biological Consequences

Published:2020-02-21 Issue:4 Volume:83 Page:1069-1081
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Tainter Craig J.¹^ORCID,Schley Nathan D.¹^ORCID,Harris Constance M.¹^ORCID,Stec Donald F.¹,Song Anna K.²,Balinski Andrzej¹^ORCID,May Jody C.¹^ORCID,McLean John A.¹^ORCID,Reece Kimberly S.²^ORCID,Harris Thomas M.¹²^ORCID

Affiliation:

1. Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States

2. Department of Aquatic Health Sciences, Virginia Institute of Marine Science, William & Mary, Gloucester Point, Virginia 23062, United States

Funder

Vanderbilt University

National Oceanic and Atmospheric Administration

National Institutes of Health

Virginia Institute of Marine Science

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.9b01094

Reference71 articles.

1. Impact of Marine Drugs on Cytoskeleton-Mediated Reproductive Events

2. Histopathological studies on experimental marine toxin poisoning—III. Morphological changes in the liver and thymus of male ICR mice induced by goniodomin A, isolated from the dinoflagellate Goniodoma pseudogoniaulax

3. Goniodomin A induces modulation of actomyosin ATPase activity mediated through conformational change of actin.

4. Goniodomin A, an Antifungal Polyether Macrolide, Increases the Filamentous Actin Content of 132IN 1 Human Astrocytoma Cells

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