A DNA Repair Inhibitor Isolated from an Ecuadorian Fungal Endophyte Exhibits Synthetic Lethality in PTEN-Deficient Glioblastoma-Reference-Cited by-同舟云学术

A DNA Repair Inhibitor Isolated from an Ecuadorian Fungal Endophyte Exhibits Synthetic Lethality in PTEN-Deficient Glioblastoma

Published:2020-05-14 Issue:6 Volume:83 Page:1899-1908
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Adaku Nneoma¹^ORCID,Park Hyun Bong²³^ORCID,Spakowicz Daniel J.⁴,Tiwari Meetu Kaushik¹,Strobel Scott A.³⁴^ORCID,Crawford Jason M.²³⁵^ORCID,Rogers Faye A.¹⁶^ORCID

Affiliation:

1. Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut 06520, United States

2. Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States

3. Chemical Biology Institute, Yale University, West Haven, Connecticut 06516, United States

4. Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520, United States

5. Department of Microbial Pathogenesis, Yale School of Medicine, New Haven, Connecticut 06536, United States

6. Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut 06520, United States

Funder

National Cancer Institute

National Institute of General Medical Sciences

Yale Comprehensive Cancer Center Swebilius Foundation

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.0c00012

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