A Screening of 10,240 NatureBank Fractions Identifies Nematicidal Activity in Agelasine-Containing Extracts from Sponges

Author:

Risi Gastón1,Liu Miaomiao2ORCID,Vairoletti Franco13ORCID,Quinn Ronald J.2ORCID,Salinas Gustavo14

Affiliation:

1. Worm Biology Lab, Institut Pasteur de Montevideo, 11400 Montevideo, Uruguay

2. Griffith Institute for Drug Discovery, Griffith University, Brisbane, Queensland 4101, Australia

3. Laboratorio de Química Farmacéutica, Departamento de Química Orgánica, Facultad de Química, Universidad de la República, 11200 Montevideo, Uruguay

4. Departamento de Biociencias, Facultad de Química, Universidad de la República, 11200 Montevideo, Uruguay

Publisher

American Chemical Society (ACS)

Reference29 articles.

1. World Health Organization Soil-Transmitted Helminth Infections. https://www.who.int/news-room/fact-sheets/detail/soil-transmitted-helminth-infections (accessed 2024–03–24).

2. Drug resistance in nematodes of veterinary importance: a status report

3. First Report of Anthelmintic Resistance in Gastrointestinal Nematodes in Goats in Romania

4. Opportunities and challenges in phenotypic drug discovery: an industry perspective

5. How were new medicines discovered?

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