Unmasking the True Identity of Rapamycin’s Minor Conformer-Reference-Cited by-同舟云学术

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Unmasking the True Identity of Rapamycin’s Minor Conformer

Published:2023-07-11 Issue:7 Volume:86 Page:1862-1869
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Crull Emily B.¹^ORCID,Jain Ajay N.²^ORCID,Hawkins Paul C. D.³,Cleves Ann E.²^ORCID,Graziani Edmund I.⁴,Williamson R. Thomas¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, University of North Carolina Wilmington, Wilmington, North Carolina 28409, United States

2. BioPharmics LLC, Santa Rosa, California 95404, United States

3. Apertor Pharmaceuticals, Inc., South San Francisco, California 94080, United States

4. Apertor Pharmaceuticals, Inc., 1640 S. Loop Rd. Suite 200, Alameda, California 94502, United States

Funder

National Science Foundation

Apertor Pharmaceuticals Inc

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.3c00421

Reference36 articles.

1. Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle.

2. Rapamycin: One Drug, Many Effects

3. Regulation and function of mTOR signalling in T cell fate decisions

4. Characterization of the FKBP·Rapamycin·FRB Ternary Complex

5. Architecture of human mTOR complex 1

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