Antitumor Activity, X-ray Crystal Structure, and DNA Binding Properties of Thiocoraline A, a Natural Bisintercalating Thiodepsipeptide-Reference-Cited by-同舟云学术

Antitumor Activity, X-ray Crystal Structure, and DNA Binding Properties of Thiocoraline A, a Natural Bisintercalating Thiodepsipeptide

Published:2007-06-16 Issue:14 Volume:50 Page:3322-3333
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Negri Ana¹,Marco Esther¹,García-Hernández Verónica¹,Domingo Alberto¹,Llamas-Saiz Antonio L.¹,Porto-Sandá Silvia¹,Riguera Ricardo¹,Laine William¹,David-Cordonnier Marie-Hélène¹,Bailly Christian¹,García-Fernández Luis F.¹,Vaquero Juan José¹,Gago Federico¹

Affiliation:

1. Departamento de Farmacología, Departamento de Bioquímica y Biología Molecular, and Departamento de Química Orgánica, Universidad de Alcalá, E-28871 Madrid, Spain, Unidad de Rayos X, Laboratorio Integral de Dinámica y Estructura de Biomoléculas José R. Carracido, Edificio CACTUS, Campus Sur, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain, Departamento de Química Orgánica, Facultad de Química, Universidad de Santiago de Compostela, E-15706 Santiago de Compostela, Spain, INSERM U...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070381s

Reference60 articles.

1. Thiocoraline, a New Depsipeptide with Antitumor Activity Produced by a Marine Micromonospora. I. Taxonomy, Fermentation, Isolation, and Biological Activities.

2. Deciphering the Biosynthesis Pathway of the Antitumor Thiocoraline from a Marine Actinomycete and Its Expression in Two Streptomyces Species

3. Mode of action of thiocoraline, a natural marine compound with anti-tumour activity

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