Tyrosine-Based 1-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) Prodrugs: Synthesis, Stability, Antiviral Activity, and in Vivo Transport Studies-Reference-Cited by-同舟云学术

Tyrosine-Based 1-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) Prodrugs: Synthesis, Stability, Antiviral Activity, and in Vivo Transport Studies

Published:2011-08-03 Issue:16 Volume:54 Page:5680-5693
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zakharova Valeria M.¹,Serpi Michaela¹,Krylov Ivan S.¹,Peterson Larryn W.¹,Breitenbach Julie M.²,Borysko Katherine Z.²,Drach John C.²,Collins Mindy³,Hilfinger John M.³,Kashemirov Boris A.¹,McKenna Charles E.¹

Affiliation:

1. Department of Chemistry, University of Southern California, Los Angeles, California 90089-0744, United States

2. School of Dentistry, University of Michigan, Ann Arbor, Michigan 48109-1078, United States

3. TSRL, Inc., Ann Arbor, Michigan 48108, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm2001426

Reference40 articles.

1. The acyclic nucleoside phosphonates from inception to clinical use: Historical perspective