Structural Basis for the Potent Antisickling Effect of a Novel Class of Five-Membered Heterocyclic Aldehydic Compounds-Reference-Cited by-同舟云学术

Structural Basis for the Potent Antisickling Effect of a Novel Class of Five-Membered Heterocyclic Aldehydic Compounds

Published:2004-08-06 Issue:19 Volume:47 Page:4665-4676
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Safo Martin K.¹,Abdulmalik Osheiza¹,Danso-Danquah Richmond¹,Burnett James C.¹,Nokuri Samuel¹,Joshi Gajanan S.¹,Musayev Faik N.¹,Asakura Toshio¹,Abraham Donald J.¹

Affiliation:

1. Department of Medicinal Chemistry, School of Pharmacy and Institute for Structural Biology and Drug Discovery, Virginia Commonwealth University, Richmond, Virginia 23298, and Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0498001

Reference41 articles.

1. Identification of a New Normal Embryonic Hæmoglobin

2. Sickle Cell Anemia, a Molecular Disease

3. Stereochemistry of Cooperative Effects in Haemoglobin: Haem–Haem Interaction and the Problem of Allostery

4. Haemoglobin: The structural changes related to ligand binding and its allosteric mechanism

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