Enabling Genetic Code Expansion and Peptide Macrocyclization in mRNA Display via a Promiscuous Orthogonal Aminoacyl-tRNA Synthetase-Reference-Cited by-同舟云学术

Enabling Genetic Code Expansion and Peptide Macrocyclization in mRNA Display via a Promiscuous Orthogonal Aminoacyl-tRNA Synthetase

Published:2023-01-11 Issue:3 Volume:145 Page:1512-1517
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Iskandar Sabrina E.¹²,Pelton Jarrett M.¹²^ORCID,Wick Elizaveta T.³⁴,Bolhuis Derek L.⁴⁵,Baldwin Albert S.⁴,Emanuele Michael J.³⁴,Brown Nicholas G.³⁴,Bowers Albert A.¹²⁶^ORCID

Affiliation:

1. Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

2. Center for Integrative Chemical Biology and Drug Discovery, Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

3. Department of Pharmacology, University of North Carolina, Chapel Hill, North Carolina 27599, United States

4. Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

5. Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina 27599, United States

6. Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

Funder

National Cancer Institute

University of North Carolina at Chapel Hill

American Cancer Society

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject