X-ray Crystal Structure of the Novel Enhanced-Affinity Glucocorticoid Agonist Fluticasone Furoate in the Glucocorticoid Receptor−Ligand Binding Domain-Reference-Cited by-同舟云学术

X-ray Crystal Structure of the Novel Enhanced-Affinity Glucocorticoid Agonist Fluticasone Furoate in the Glucocorticoid Receptor−Ligand Binding Domain

Published:2008-06-01 Issue:12 Volume:51 Page:3349-3352
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Biggadike Keith¹,Bledsoe Randy K.¹,Hassell Anne M.¹,Kirk Barrie E.¹,McLay Iain M.¹,Shewchuk Lisa M.¹,Stewart Eugene L.¹

Affiliation:

1. Departments of Computational Chemistry and Medicinal Chemistry, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, U.K., and Departments of Computational Chemistry and Structural Biology, GlaxoSmithKline, 5 Moore Drive, Research Triangle Park, North Carolina 27709

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800279t

Reference29 articles.

1. Fluticasone Furoate

2. Fluticasone furoate nasal spray: A single treatment option for the symptoms of seasonal allergic rhinitis

3. Once daily fluticasone furoate nasal spray is effective in seasonal allergic rhinitis caused by grass pollen

4. Absolute Bioavailability of Intranasal Fluticasone Furoate in Healthy Subjects

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