Qualitative Analysis of the Role of Metabolites in Inhibitory Drug−Drug Interactions: Literature Evaluation Based on the Metabolism and Transport Drug Interaction Database-Reference-Cited by-同舟云学术

Qualitative Analysis of the Role of Metabolites in Inhibitory Drug−Drug Interactions: Literature Evaluation Based on the Metabolism and Transport Drug Interaction Database

Published:2009-02-16 Issue:2 Volume:22 Page:294-298
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Isoherranen Nina¹,Hachad Houda¹,Yeung Catherine K.¹,Levy Rene H.¹

Affiliation:

1. Department of Pharmaceutics, University of Washington, P.O. Box 357610, Seattle, Washington 98195

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx800491e

Reference13 articles.

1. U.S. Food and Drug Administration (2008)Guidance for Industry. Safety Testing of Drug Metabolites, FDA, Rockville, MD.

2. U.S. Food and Drug Adminstration (2006)Guidance for Industry Drug Interaction Studies — Study Design, Data Analysis, and Implications for Dosing and Labeling. Draft Guidance, FDA, Rockville, MD.

3. Metabolites and Safety: What Are the Concerns, and How Should We Address Them?

4. Prediction of In Vivo Drug-Drug Interactions from In Vitro Data

5. The Utility of in Vitro Cytochrome P450 Inhibition Data in the Prediction of Drug-Drug Interactions

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