Secondary Mutations M36I and A71V in the Human Immunodeficiency Virus Type 1 Protease Can Provide an Advantage for the Emergence of the Primary Mutation D30N-Reference-Cited by-同舟云学术

Secondary Mutations M36I and A71V in the Human Immunodeficiency Virus Type 1 Protease Can Provide an Advantage for the Emergence of the Primary Mutation D30N

Published:2003-12-01 Issue:51 Volume:42 Page:15029-15035
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Clemente José C.¹,Hemrajani Reena¹,Blum Lisa E.¹,Goodenow Maureen M.¹,Dunn Ben M.¹

Affiliation:

1. Departments of Biochemistry and Molecular Biology and of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida 32610

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi035701y

Reference51 articles.

1. A Controlled Trial of Two Nucleoside Analogues plus Indinavir in Persons with Human Immunodeficiency Virus Infection and CD4 Cell Counts of 200 per Cubic Millimeter or Less

2. Escape mutants of HIV-1 proteinase: enzymic efficiency and susceptibility to inhibition

3. Non-active Site Changes Elicit Broad-based Cross-resistance of the HIV-1 Protease to Inhibitors

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