Structural Basis for the Interaction of Lactivicins with Serine β-Lactamases
Author:
Affiliation:
1. Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, U.K.
2. Centre d’Ingénierie des Protéines, Université de Liège, B-4000 Sart Tilman, Liège, Belgium
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm100437u
Reference35 articles.
1. The penicillin-binding proteins: structure and role in peptidoglycan biosynthesis
2. Penicillin-binding proteins and β-lactam resistance
3. Structure of lactivicin, an antibiotic having a new nucleus and similar biological activities to β-lactam antibiotics
4. Chemistry of a new antibiotic: lactivicin
5. Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-D-alanyl-D-alanine.
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