Hybrid Modeling of CHO Cell Cultivation in Monoclonal Antibody Production with an Impurity Generation Module
Author:
Affiliation:
1. Department of Chemical System Engineering, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, 113-8656 Tokyo, Japan
2. Manufacturing Technology Association of Biologics, 2-6-16, Shinkawa, Chuo-ku, 104-0033 Tokyo, Japan
Funder
Japan Agency for Medical Research and Development
Publisher
American Chemical Society (ACS)
Subject
Industrial and Manufacturing Engineering,General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.iecr.2c00736
Reference30 articles.
1. Comparison between Batch and Continuous Monoclonal Antibody Production and Economic Analysis
2. A PSE perspective for the efficient production of monoclonal antibodies: integration of process, cell, and product design aspects
3. A common framework for integrated and continuous biomanufacturing
4. Effective temperature shift strategy development and scale confirmation for simultaneous optimization of protein productivity and quality in Chinese hamster ovary cells
5. Strategies to enhance productivity and modify product quality in therapeutic proteins
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