Discovery of Octahydroindenes as PAR1 Antagonists
Author:
Affiliation:
1. Division of Drug Discovery Research, Korea Research Institute of Technology, 141 Gajeongno, Yuseong, Deajeon 305-600, Korea
2. R&D Park, LG Life Sciences, 104-1 Munji-Dong, Yuseong, Deajeon 305-380, Korea
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ml400235c
Reference30 articles.
1. Thrombin signalling and protease-activated receptors
2. Targeting proteinase-activated receptors: therapeutic potential and challenges
3. Protease-activated receptors in hemostasis, thrombosis and vascular biology
4. Domains specifying thrombin–receptor interaction
5. Thrombin receptor activation. Confirmation of the intramolecular tethered liganding hypothesis and discovery of an alternative intermolecular liganding mode.
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