Multiple Adduction Reactions of Nitroso Sulfamethoxazole with Cysteinyl Residues of Peptides and Proteins: Implications for Hapten Formation-Reference-Cited by-同舟云学术

Multiple Adduction Reactions of Nitroso Sulfamethoxazole with Cysteinyl Residues of Peptides and Proteins: Implications for Hapten Formation

Published:2009-04-09 Issue:5 Volume:22 Page:937-948
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Callan Hayley E.¹,Jenkins Rosalind E.¹,Maggs James L.¹,Lavergne Sidonie N.¹,Clarke Stephen E.¹,Naisbitt Dean J.¹,Park B. Kevin¹

Affiliation:

1. MRC Centre for Drug Safety Science, Department of Pharmacology and Therapeutics, School of Biomedical Sciences, The University of Liverpool, Liverpool L69 3GE, and DMPK, GlaxoSmithKline, Ware, Hertfordshire SG12 0DP, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx900034r

Reference58 articles.

1. Trimethoprim–sulfamethoxazole induced rash and fatal hematologic disorders

2. Cholestatic hepatitis with severe systemic reactions induced by trimethoprim-sulfamethoxazole

3. Drug hypersensitivity reactions in skin: understanding mechanisms and the development of diagnostic and predictive tests

4. Toxic epidermal necrolysis: Effector cells are drug-specific cytotoxic T cells

5. HIV and drug allergy

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