In Search of a Novel Anti-HIV Drug: Multidisciplinary Coordination in the Discovery of 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, Rilpivirine)-Reference-Cited by-同舟云学术

In Search of a Novel Anti-HIV Drug: Multidisciplinary Coordination in the Discovery of 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, Rilpivirine)

Published:2004-11-06 Issue:6 Volume:48 Page:1901-1909
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Janssen Paul A. J.¹,Lewi Paul J.¹,Arnold Eddy¹,Daeyaert Frits¹,de Jonge Marc¹,Heeres Jan¹,Koymans Luc¹,Vinkers Maarten¹,Guillemont Jérôme¹,Pasquier Elisabeth¹,Kukla Mike¹,Ludovici Don¹,Andries Koen¹,de Béthune Marie-Pierre¹,Pauwels Rudi¹,Das Kalyan¹,Clark, Art D.¹,Frenkel Yulia Volovik¹,Hughes Stephen H.¹,Medaer Bart¹,De Knaep Fons¹,Bohets Hilde¹,De Clerck Fred¹,Lampo Ann¹,Williams Peter¹,Stoffels Paul¹

Affiliation:

1. Center for Molecular Design, Janssen Pharmaceutica, B-2350 Vosselaar, Belgium; Center for Advanced Biotechnology and Medicine, and Department of Chemistry, and Chemical Biology, Rutgers University, Piscataway, New Jersey 08854; Medicinal Chemistry, Johnson & Johnson Pharmaceutical Research & Development, Janssen-Cilag France, F-27106 Val de Reuil Cedex, France; Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, Spring House, Pennsylvania 19477; Tibotec, B-2800 Mechelen, Belgium;...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm040840e

Reference60 articles.

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