Poly(glycoamidoamine) Brushes Formulated Nanomaterials for Systemic siRNA and mRNA Delivery in Vivo

Author:

Dong Yizhou12,Dorkin J. Robert,Wang Weiheng12,Chang Philip H.12,Webber Matthew J.12,Tang Benjamin C.12,Yang Junghoon1,Abutbul-Ionita Inbal3,Danino Dganit3,DeRosa Frank4,Heartlein Michael4,Langer Robert12,Anderson Daniel G.12

Affiliation:

1. David H. Koch Institute for Integrative Cancer Research, ‡Department of Chemical Engineering, §Department of Biology, and ∥Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States

2. Department of Anesthesiology, Children’s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, United States

3. Department of Biotechnology and Food Engineering, Technion Institute of Technology and the Russell Berrie Nanotechnology Institute, Haifa 32000, Israel

4. Shire, 300 Shire Way, Lexington, Massachusetts 02421, United States

Funder

National Cancer Institute

National Heart, Lung, and Blood Institute

National Institute of Dental and Craniofacial Research

National Institute of Biomedical Imaging and Bioengineering

Shire

Alnylam Pharmaceuticals, Inc.

Publisher

American Chemical Society (ACS)

Subject

Mechanical Engineering,Condensed Matter Physics,General Materials Science,General Chemistry,Bioengineering

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