New Straightforward Synthesis and Characterization of a Unique 1β-Methylcarbapenem Antibiotic Biapenem Bearing a σ-Symmetric Bicyclotriazoliumthio Group as the Pendant Moiety-Reference-Cited by-同舟云学术

New Straightforward Synthesis and Characterization of a Unique 1β-Methylcarbapenem Antibiotic Biapenem Bearing a σ-Symmetric Bicyclotriazoliumthio Group as the Pendant Moiety

Published:1998-10-16 Issue:23 Volume:63 Page:8145-8149
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Kumagai Toshio¹,Tamai Satoshi¹,Abe Takao¹,Matsunaga Hiroshi¹,Hayashi Kazuhiko¹,Kishi Ikuo¹,Shiro Motoo¹,Nagao Yoshimitsu¹

Affiliation:

1. The Chemical and Formulation Research Laboratories, Lederle (Japan), Ltd., Kashiwa-cho, Shiki, Saitama 353-8511, Japan, Rigaku Corporation, 3-9-12 Matsubara-cho, Akishima-shi, Tokyo 196-8666, Japan, and Faculty of Pharmaceutical Sciences, The University of Tokushima, Sho-machi, Tokushima 770-8505, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo980462j

Reference21 articles.

1. Synthetic Carbapenem Antibiotics. I. 1-b-Methylcarbapenem

2. A novel carbapenem antibiotic, SM-7338 structure-activity relationships.

3. .beta.-Lactams. 3. Asymmetric total synthesis of new non-natural 1.beta.-methylcarbapenems exhibiting strong antimicrobial activities and stability against human renal dehydropeptidase-I

4. 1,a-Methyl-2-(5-substituted pyrrolidin-3-ylthio)carbapenems; 3. Synthesis and Antibacterial Activity of BO-2727 and Its Related Compounds.

5. Heteroaryliumthio substituted carbapenem derivatives: Synthesis and in vitro activity of 1.BETA.-methyl-2-(dihydropyrrolotriazoliumthio)carbapenems.

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