Benzimidazole Derivatives Bearing Substituted Biphenyls as Hepatitis C Virus NS5B RNA-Dependent RNA Polymerase Inhibitors: Structure−Activity Relationship Studies and Identification of a Potent and Highly Selective Inhibitor JTK-109-Reference-Cited by-同舟云学术

Benzimidazole Derivatives Bearing Substituted Biphenyls as Hepatitis C Virus NS5B RNA-Dependent RNA Polymerase Inhibitors: Structure−Activity Relationship Studies and Identification of a Potent and Highly Selective Inhibitor JTK-109

Published:2006-06-28 Issue:15 Volume:49 Page:4721-4736
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hirashima Shintaro¹,Suzuki Takayoshi¹,Ishida Tomio¹,Noji Satoru¹,Yata Shinji¹,Ando Izuru¹,Komatsu Masakazu¹,Ikeda Satoru¹,Hashimoto Hiromasa¹

Affiliation:

1. Central Pharmaceutical Research Institute, Japan Tobacco Inc., 1-1 Murasaki-cho, Takatsuki, Osaka 569-1125, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm060269e

Reference26 articles.

1. Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: Identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole

2. An Assay for Circulating Antibodies to a Major Etiologic Virus of Human Non-A, Non-B Hepatitis

3. Candidate Targets for Hepatitis C Virus-Specific Antiviral Therapy

4. Hepatitis C virus (HCV) NS5A protein: role in HCV replication and resistance to interferon‐α

Cited by 158 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A Comprehensive Review of the Benzimidazole Scaffold as a Potential Nucleus for Anti-Ulcer Activity;Letters in Organic Chemistry;2024-06

2. Supramolecular complex assembly with build-in light-harvesting antenna enables efficient photocatalytic synthesis of benzimidazoles;Journal of Organometallic Chemistry;2024-06

3. Transition‐Metal Free Arylation of Therapeutically Important Heterocycles;ChemistrySelect;2024-05-15

4. N-Heterocycles as Promising Antiviral Agents: A Comprehensive Overview;Molecules;2024-05-10

5. Total Synthesis of a Pancratistatin/Shikimic Acid Hybrid Analogue;European Journal of Organic Chemistry;2024-01-29