Streamlined Processes for the Synthesis of a Farnesyl Transferase Inhibitor Drug Candidate-Reference-Cited by-同舟云学术

Streamlined Processes for the Synthesis of a Farnesyl Transferase Inhibitor Drug Candidate

Published:2004-06-26 Issue:4 Volume:8 Page:643-650
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Andresen Brian M.¹,Couturier Michel¹,Cronin Brian¹,D'Occhio Michael¹,Ewing Marcus D.¹,Guinn Mark¹,Hawkins Joel M.¹,Jasys V. John¹,LaGreca Susan D.¹,Lyssikatos Joseph P.¹,Moraski Garrett¹,Ng Karl¹,Raggon Jeffrey W.¹,Stewart A. Morgan¹,Tickner Derek L.¹,Tucker John L.¹,Urban Frank J.¹,Vazquez Enrique¹,Wei Lulin¹

Affiliation:

1. Pfizer Inc., Eastern Point Road, Groton, Connecticut 06340, U.S.A.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op049935g

Reference6 articles.

1. Selective Inhibition of ras -Dependent Transformation by a Farnesyltransferase Inhibitor

2. 57. Alkylation of the aromatic nucleus. Part VIII. Benzylation and cyclohexylmethylation

3. Models for metal binding sites in zinc enzymes. Syntheses of tris[4(5)-imidazolyl]carbinol (4-TIC), tris(2-imidazolyl)carbinol (2-TIC), and related ligands, and studies on metal complex binding constants and spectra

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