8-Tetrahydropyran-2-yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors-Reference-Cited by-同舟云学术

8-Tetrahydropyran-2-yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors

Published:2014-11-26 Issue:23 Volume:57 Page:10112-10129
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Thomas Allen A.¹,Hunt Kevin W.¹,Newhouse Brad¹,Watts Ryan J.²,Liu Xingrong²,Vigers Guy¹,Smith Darin¹,Rhodes Susan P.¹,Brown Karin D.¹,Otten Jennifer N.¹,Burkard Michael¹,Cox April A.¹,Geck Do Mary K.¹,Dutcher Darrin¹,Rana Sumeet¹,DeLisle Robert K.¹,Regal Kelly¹,Wright Albion D.¹,Groneberg Robert¹,Liao Jiangpeng³,Scearce-Levie Kimberly²,Siu Michael²,Purkey Hans E.²,Lyssikatos Joseph P.²

Affiliation:

1. Array BioPharma, 3200 Walnut Street, Boulder, Colorado 80301, United States

2. Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States

3. WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, P. R. China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm5015132

Reference56 articles.

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