Structure−Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Further Investigation on the Inner Spacer-Reference-Cited by-同舟云学术

Structure−Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Further Investigation on the Inner Spacer

Published:2008-10-28 Issue:22 Volume:51 Page:7308-7312
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Tumiatti Vincenzo¹,Milelli Andrea¹,Minarini Anna¹,Rosini Michela¹,Bolognesi Maria Laura¹,Micco Marialuisa¹,Andrisano Vincenza¹,Bartolini Manuela¹,Mancini Francesca¹,Recanatini Maurizio¹,Cavalli Andrea¹,Melchiorre Carlo¹

Affiliation:

1. Department of Pharmaceutical Sciences, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy, and Polo Scientifico-Didattico di Rimini, University of Bologna, 40100 Bologna, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm8009684

Reference30 articles.

1. Disease-modifying therapies for Alzheimer disease: Challenges to early intervention

2. Beyond symptomatic therapy: a re-examination of acetylcholinesterase inhibitors in Alzheimer’s disease

3. Targeting acetylcholinesterase to treat neurodegeneration

4. Novel cholinesterase inhibitors as future effective drugs for the treatment of Alzheimer’s disease

5. Multifunctional drugs with different CNS targets for neuropsychiatric disorders

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