Synthesis, Biological Evaluation, and Structure−Activity Relationships for 5-[(E)-2-Arylethenyl]-3-isoxazolecarboxylic Acid Alkyl Ester Derivatives as Valuable Antitubercular Chemotypes

Author:

Pieroni Marco1,Lilienkampf Annamaria1,Wan Baojie2,Wang Yuehong2,Franzblau Scott G.2,Kozikowski Alan P.1

Affiliation:

1. Drug Discovery Program, Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612

2. Institute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference32 articles.

1. World Health Organization. Global Tuberculosis Control—Surveillance, Planning, Financing;World Health Organization:Geneva, 2008; http://www.who.int/tb/publications/global_report/en/index.html(accessed February 2009) .

2. HIV‐Associated Opportunistic Infections—Going, Going, But Not Gone: The Continued Need for Prevention and Treatment Guidelines

3. New drug candidates and therapeutic targets for tuberculosis therapy

4. New anti-tuberculosis drugs in clinical trials with novel mechanisms of action

5. Tuberculosis Chemotherapy

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