Alternative Synthesis of Septic Shock Candidate 3,4-Dihydro-3,3-dimethylisoquinoline N-Oxide (MDL 101002) Utilizing an Improved Pictet−Spengler Reaction-Reference-Cited by-同舟云学术

Alternative Synthesis of Septic Shock Candidate 3,4-Dihydro-3,3-dimethylisoquinoline N-Oxide (MDL 101002) Utilizing an Improved Pictet−Spengler Reaction

Published:1998-01-01 Issue:2 Volume:63 Page:406-407
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Watson Timothy J. N.¹

Affiliation:

1. Chemical Development, Hoechst Marion Roussel Research Institute, 2110 East Galbraith Road, Cincinnati, Ohio 45215-6300

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo9718004

Reference14 articles.

1. Synthesis and radical scavenging activity of 3,3-dialkyl-3,4-dihydro-isoquinoline 2-oxides

2. A modified Bischler-Napieralski procedure for the synthesis of 3-aryl-3,4-dihydroisoquinolines

3. (d) Thomas, C. E.; Carney, J. M.; Bernotas, R. C.; Hay, D. A.; Carr, A. A.Neurobiol. No Oh1994,738, 243−249.

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