Enantioselective Pd-Catalyzed α-Arylation of N-Boc-Pyrrolidine: The Key to an Efficient and Practical Synthesis of a Glucokinase Activator-Reference-Cited by-同舟云学术

Enantioselective Pd-Catalyzed α-Arylation of N-Boc-Pyrrolidine: The Key to an Efficient and Practical Synthesis of a Glucokinase Activator

Published:2008-05-29 Issue:13 Volume:73 Page:4986-4993
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Klapars Artis¹,Campos Kevin R.¹,Waldman Jacob H.¹,Zewge Daniel¹,Dormer Peter G.¹,Chen Cheng-yi¹

Affiliation:

1. Department of Process Research, Merck Research Laboratories, Rahway, New Jersey 07065

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo8006804

Reference25 articles.

1. Selective Hydrogenation for Fine Chemicals: Recent Trends and New Developments

2. Nonoshita, K.; Ogino, Y.; Ishikawa, M.; Sakai, F.; Nakashima, H.; Nagae, Y.; Tsukahara, D.; Arakawa, K.; Nishimura, T.; Eiki, J.Patent Application WO 2005063738.

3. Enantioselective, Palladium-Catalyzed α-Arylation of N-Boc-pyrrolidine

4. A rapid and general method for the asymmetric synthesis of 2-substituted pyrrolidines using tert-butanesulfinamide

5. Asymmetric titanocene-catalyzed hydrogenation of imines

Cited by 68 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A new β-carboline-type alkaloid from the flowers of Calotropis gigantea (L.) W.T.Aiton;Natural Product Research;2023-05-02

2. Iridium-Catalyzed Enantioselective Direct α-C–H Alkylation of Saturated Cyclic Amines with Alkenes;Organic Letters;2022-09-15

3. Large-Scale Amidations in Process Chemistry: Practical Considerations for Reagent Selection and Reaction Execution;Organic Process Research & Development;2022-06-07

4. A directing group switch in copper-catalyzed electrophilic C–H amination/migratory annulation cascade: divergent access to benzimidazolone/benzimidazole;Chemical Science;2022

5. Industrial Applications of Transition Metal-Catalyzed Asymmetric Cross-Coupling Reactions (C–C and C–N Bond Formations);Reference Module in Chemistry, Molecular Sciences and Chemical Engineering;2022