Insights into the Acylation Mechanism of Class A β-Lactamases from Molecular Dynamics Simulations of the TEM-1 Enzyme Complexed with Benzylpenicillin-Reference-Cited by-同舟云学术

Insights into the Acylation Mechanism of Class A β-Lactamases from Molecular Dynamics Simulations of the TEM-1 Enzyme Complexed with Benzylpenicillin

Published:2002-12-24 Issue:3 Volume:125 Page:672-684
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Díaz Natalia¹,Sordo Tomás L.¹,Merz Kenneth M.¹,Suárez Dimas¹

Affiliation:

1. Contribution from the Departamento de Química Física y Analítica, Universidad de Oviedo, C/ Julián Clavería 8, 33006 Oviedo, Spain, and Department of Chemistry, The Pennsylvania State University, 152 Davey Laboratory, University Park, Pennsylvania 16802-6300 USA

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja027704o

Reference71 articles.

1. Molecular mechanisms that confer antibacterial drug resistance

2. Resisting resistance: new chemical strategies for battling superbugs

3. Waley, S. G. β-Lactamases:MechanismofAction; Page, M. I., Ed.; Blackie Academic & Professional: London, 1992; pp 199−227.

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