Structural Basis for the Selective Inhibition of HDAC10, the Cytosolic Polyamine Deacetylase-Reference-Cited by-同舟云学术

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Structural Basis for the Selective Inhibition of HDAC10, the Cytosolic Polyamine Deacetylase

Published:2020-07-13 Issue:8 Volume:15 Page:2154-2163
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Herbst-Gervasoni Corey J.¹,Steimbach Raphael R.²³,Morgen Michael³,Miller Aubry K.³⁴^ORCID,Christianson David W.¹^ORCID

Affiliation:

1. Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States

2. Biosciences Faculty, University of Heidelberg, 69120 Heidelberg, Germany

3. Cancer Drug Development Group, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany

4. German Cancer Consortium (DKTK), 69120 Heidelberg, Germany

Funder

National Institutes of Health

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.0c00362

Reference30 articles.

1. Molecular Evolution of the Histone Deacetylase Family: Functional Implications of Phylogenetic Analysis

2. The many roles of histone deacetylases in development and physiology: implications for disease and therapy

3. Structure, mechanism, and inhibition of the zinc-dependent histone deacetylases

4. Polyamine Deacetylase Structure and Catalysis: Prokaryotic Acetylpolyamine Amidohydrolase and Eukaryotic HDAC10

5. Histone deacetylase 10 structure and molecular function as a polyamine deacetylase

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1. Design, Synthesis, and Structural Evaluation of Acetylated Phenylthioketone Inhibitors of HDAC10;ACS Medicinal Chemistry Letters;2024-09-05

2. Targeting histone deacetylases: Emerging applications beyond cancer;Drug Discovery Today;2024-09

3. Elevated N1-Acetylspermidine Levels in Doxorubicin-treated MCF-7 Cancer Cells: Histone Deacetylase 10 Inhibition with an N1-Acetylspermidine Mimetic;Journal of Cancer Prevention;2024-06-30

4. Chemical Versatility in Catalysis and Inhibition of the Class IIb Histone Deacetylases;Accounts of Chemical Research;2024-03-26

5. Histone deacetylase 10: A polyamine deacetylase from the crystal structure to the first inhibitors;Current Opinion in Structural Biology;2023-10

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