Polypharmacological in Silico Bioactivity Profiling and Experimental Validation Uncovers Sedative-Hypnotic Effects of Approved and Experimental Drugs in Rat-Reference-Cited by-同舟云学术

Polypharmacological in Silico Bioactivity Profiling and Experimental Validation Uncovers Sedative-Hypnotic Effects of Approved and Experimental Drugs in Rat

Published:2017-05-01 Issue:6 Volume:12 Page:1593-1602
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Drakakis Georgios¹,Wafford Keith A.²,Brewerton Suzanne C.²,Bodkin Michael J.²,Evans David A.²,Bender Andreas¹^ORCID

Affiliation:

1. Centre for Molecular Informatics, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom

2. Eli Lilly U.K., Erl Wood Manor, Windlesham, Surrey GU206PH, United Kingdom

Funder

Engineering and Physical Sciences Research Council

Unilever

Eli Lilly and Company

H2020 European Research Council

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.7b00209

Reference54 articles.

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