Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation-Reference-Cited by-同舟云学术

Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation

Published:2024-02-02 Issue:2 Volume:19 Page:442-450
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Hong Seong Ho¹²^ORCID,Divakaran Anand¹²,Osa Akane¹²,Huang Oscar W.³,Wertz Ingrid E.³,Nomura Daniel K.¹²⁴^ORCID

Affiliation:

1. Department of Chemistry, University of California, Berkeley, 2151 Berkeley Way, Room 312G, Berkeley, California 94720, United States

2. Innovative Genomics Institute, 2151 Berkeley Way, Berkeley, California 94720, United States

3. Bristol Myers Squibb, 700 Bay Road, Redwood City, California 94063, United States

4. Department of Molecular and Cell Biology, University of California, Berkeley, 2151 Berkeley Way, Room 312G, Berkeley, California 94720, United States

Funder

Division of Chemistry

National Cancer Institute

Bristol-Myers Squibb

Mark Foundation For Cancer Research

Nomura Research Group

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.3c00642

Reference31 articles.

1. Ligandability of E3 Ligases for Targeted Protein Degradation Applications

2. Targeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α Interaction

3. Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4

4. Phthalimide conjugation as a strategy for in vivo target protein degradation

5. Development of hybrid small molecules that induce degradation of estrogen receptor-alpha and necrotic cell death in breast cancer cells

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