Small-Molecule Inhibition of the C. difficile FAS-II Enzyme, FabK, Results in Selective Activity-Reference-Cited by-同舟云学术

Small-Molecule Inhibition of the C. difficile FAS-II Enzyme, FabK, Results in Selective Activity

Published:2019-06-11 Issue:7 Volume:14 Page:1528-1535
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Jones Jesse A.¹^ORCID,Prior Allan M.²^ORCID,Marreddy Ravi K. R.³^ORCID,Wahrmund Rebecca D.¹,Hurdle Julian G.³^ORCID,Sun Dianqing²^ORCID,Hevener Kirk E.¹^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States

2. Department of Pharmaceutical Sciences, The Daniel K. Inouye College of Pharmacy, University of Hawaii at Hilo, Hilo, Hawaii, 96720, United States

3. Center for Infectious and Inflammatory Diseases, Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, Texas 77030, United States

Funder

National Institute of Allergy and Infectious Diseases

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.9b00293

Reference52 articles.

1. Clostridioides (Clostridium) difficile infection: current and alternative therapeutic strategies

2. Burden of Clostridium difficile on the Healthcare System

3. Current Status of Clostridium difficile Infection Epidemiology