Adenylation Domain-Guided Recruitment of Trans-Acting Nonheme Monooxygenases in Nonribosomal Peptide Biosynthesis
Author:
Affiliation:
1. Institute of Pharmaceutical Biology, University of Bonn, Nussallee 6, 53115 Bonn, Germany
2. Institute of Structural Biology, University of Bonn, Venusberg-Campus 1, 53127 Bonn, Germany
Funder
Deutsche Forschungsgemeinschaft
Publisher
American Chemical Society (ACS)
Subject
Molecular Medicine,General Medicine,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acschembio.3c00106
Reference44 articles.
1. Nonribosomal Peptide Synthesis-Principles and Prospects
2. Activation of the Pacidamycin PacL Adenylation Domain by MbtH-like Proteins
3. MbtH-Like Proteins as Integral Components of Bacterial Nonribosomal Peptide Synthetases
4. Role of MbtH-like Proteins in the Adenylation of Tyrosine during Aminocoumarin and Vancomycin Biosynthesis
5. Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359
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